Hartley, who played a key role in England’s World Cup win last summer, has been replaced by fellow left-arm spinner Sophie Ecclestone after the latter took eight wickets in three ODIs against India in April.

Meanwhile England welcome back Katherine Brunt, who was ruled out of the India tour through injury, and Sarah Taylor, who was rested.

The South Africa series, which begins with matches at Worcestershire and Hove, is part of the ICC Women’s Championship, which decides the qualifiers for the 2021 Women’s World Cup in New Zealand, with England currently in sixth position in the points table.

Twill be the first meeting between the two sides since they contested the World Cup semi-final at Bristol last year.

Following the South Africa series, both teams will compete in an IT20 tri-series alongside New Zealand, before England play another three ICC Women’s Championship fixtures against the Kiwis in early July.

England Women’s squad to face South Africa

Heather Knight (captain, Berkshire)
Tammy Beaumont (Kent)
Katherine Brunt (Yorkshire)
Sophie Ecclestone (Lancashire)
Georgia Elwiss (Sussex)
Jenny Gunn (Warwickshire)
Danielle Hazell (Yorkshire)
Amy Jones (wicketkeeper, Warwickshire)
Laura Marsh (Kent)
Anya Shrubsole (Somerset)
Nat Sciver (Surrey)
Sarah Taylor (wicketkeeper, Sussex)
Lauren Winfield (Yorkshire)
Danni Wyatt (Sussex)

Fixtures

Saturday June 9: 1st ODI v South Africa, Blackfinch New Road, 11am
Tuesday June 12: 2nd ODI v South Africa, 1st Central County Ground, 1pm
Friday June 15: 3rd ODI v South Africa, Spitfire Ground, St Lawrence, 2pm